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Review Article
Clinical Medicine
Medical Genetics

An integrated route to identifying new pathogenesis-based therapeutic approaches for trisomy 21 (Down Syndrome) following the thought of Jérôme Lejeune

Pierluigi Strippoli1*, Maria Chiara Pelleri11*, Maria Caracausi1, Lorenza Vitale1, Allison Piovesan1, Chiara Locatelli2, Maria Chiara Mimmi3, Anna Concetta Berardi4, Doris Ricotta5, Annalisa Radeghieri5, Donatella Barisani6, Mark Basik7, Maria Chiara Monaco8, Alessandro Ghezzo1, Marco Seri9, Guido Cocchi10